these houses are called so, as they create so much difficulties in our material life.
but if you look at the positive side of it, these stressful houses give us enough opportunities to feel helplessly lost that you even stop looking for divine help!
but then with the support of 5th and 9th houses, the houses of wisdom and house of dharma,
sub-consciously you reach a phase that grace manifests by itself.
and you arrive!
take the case of ramana, osho, paramahamsa yogananda, swami rama..all these great masters' horoscopes had dusthanas in full action.
now, that's a real inspiration, isn't it?